Travel to Mars - on a one-way ticket?, Houston Chronicle
"A blue-ribbon panel on human spaceflight recently declared Mars to be NASA's ultimate objective, but admitted humans aren't going there any time soon. In fact, the Augustine panel appointed by President Barack Obama said that without a substantial infusion of cash, NASA couldn't even send humans back to the moon in the next few decades. Depressing news, indeed, for the city that trains and houses astronauts. But what if NASA could land astronauts on Mars in a decade, for not ridiculously more money than the $10 billion the agency spends annually on human spaceflight? It's possible, say some space buffs, although there's a catch. The astronauts we'd send would never come home."


I suggested this back in 1997 when the folk at Johnson were, with a straight face, talking about a 2009 first launch for a crewed mission to Mars. However I further calculated that a crew of six could be provided with keep-alive supplies indefinitely for about half a billion dollars a year (would need to be adjusted for inflation and current launch costs). Then they can just live there (in their dirt-covered habitat to protect against radiation) until someone develops their ride home.
So maybe they could come home eventually. If they wanted.